MUKORMIKOSIS KUTAN PADA ANAK: TINJAUAN PUSTAKA
DOI:
https://doi.org/10.33820/mdvi.v49i3.308Keywords:
manifestasi kulit, mukormikosis kutanAbstract
Mukormikosiskutanpadaanakadalahinfeksijamur Mucor sp. yangdapatmenyebabkanbeberapa komplikasi dan kematian dengan angka morbiditas dan mortalitas yang cukup tinggi.Tinjauan pustaka ini bertujuanuntukmengenaldanmemahamigambaranklinisbeberapakelainankulitakibatmukormikosis kutanpadaanak,melakukanpenegakandiagnosissertamemberikantatalaksanayangtepat.Pencarian literaturmenggunakanpedoman Preferred reporting items for systemic reviews and meta analyses (PRISMA)melaluibasisdata PubMed dan Science Direct padabulanApril2020.Sejumlah15artikel termasukdalamtinjauanpustakaini.Mukormikosiskutanpadaanakadalahsuatuinfeksijamur oportunistikyangdisebabkanolehjamurMucor sp.,penyakitinidapatmenjadiinfeksiprimeratau sebuahmanifestasiklinissebagaico-infection pada underlying disease lainnya. Ujud kelainankulit pada mukormikosis kutan memiliki kesamaan padainfeksi jamurlainnya, sehinggaperlu dilakukan pemeriksaan kultur danhistopatologi sebagaibaku emas untukmenegakkandiagnosis.Manifestasi klinis kelainankulitdapatsalingtumpangtindihdenganbeberapainfeksikulityangdisebabkanolehjamur, namunpadamukormikosiskutanmemilikigejalayangkhas.Padapasienanak-anak,perludilakukan pemeriksaansecaraintensifdanmenyeluruh,anamnesisgejalapenyakitdanriwayatpenyakityangdapat menjadi underlying disease yang dapat menyebabkan terjadinya mukormikosis kutan. Kata Kunci: manifestasi kulit, mukormikosis kutan.Downloads
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References
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ment. J Pediatric Infect Dis. 2018; 7(2):159-64.
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N, Brumble L, dkk. Stability in the cumulative incidence, se- verity and mortality of 101 cases of invasive mucormycosis in high risk patients from 1995 to 2021 : a comparison of eras immediately before and after the availability of variconazole and echinocandin-amphotericin combination therapies. 2014; 57(11): 687–98.
23. Garbino J, Myers C, Ambrosioni J, Gumy-pause F. Report of a Successful Treatment of Pulmonary Cunninghamella bertholletiae Infection With Liposomal Amphotericin and Posaconazole in a Child With GvHD and Review of the Lit- erature. 2010; 32(2): 85–7.
24. Cornely OA, Dannaoui E, Groll AH, Lagrou K, Chakrabar- ti A, Lanternier F, dkk. ESCMID and ECMM joint clinical guidelines for the diagnosis and management of mucormyco- sis 2013. 2014; 20(3): 5–26.
2. Jeong W, Keighley C, Wolfe R, Lee WL, Slavin MA, Kong DCM, dkk. The epidemiology and clinical manifestations of mucormycosis: A systematic review and meta-analysis of case reports. Clin Microbiol Infect 2019; 25(1): 26–34.
3. Petrikkos G. Challenges in the diagnosis and treatment of mu- cormycosis. 2018; 56(1): 93–101.
4. Chu JH, Walsh TJ. Zygomycosis in Children: A Systematic Review and Analysis of Reported Cases. 2017; 26(8): 723–7.
5. Skiada A, Pavleas I, Drogari-Apiranthitou M. Epidemiology and Diagnosis of Mucormycosis: An Update. Clin Infect Dis.
2020; 6(4): 1–20.
6. Prasad PA, Vaughan AM, Zaoutis TE. Trends in zygomycosis
in children. 2010: 55(4): 1–5.
7. Foster CE, Revell PA, Campbell JR, Marquez L. Healthcare-
associated Pediatric Cutaneous Mucormycosis at Texas Chil- dren’s Hospital, 2012–2019. Pediatr Infect Dis J. 2021; 40(8): 2019–21.
8. Pana ZD, Seidel D, Skiada A, Groll AH, Petrikkos G, Cornely OA. Invasive mucormycosis in children: an epidemiologic study in European and non- European countries based on two registries. BMC Infect Dis. 2016; 16(1): 1–9.
9. Galletti B, Gazia F, Freni F, Galletti C. Rhinocerebral mu- cormycosis with dissemination to pontine area in a diabetic patient: Treatment and management. 2019; 7(7): 1382–7.
10. GarcÃa-sepúlveda R, Navarrete-solÃs J, Villanueva-lozano H, J R De, González GM, EnrÃquez-rojas J, dkk. photoletter to the editor: Atypical primary cutaneous mucormycosis of the scalp. 2017; 11(2): 32–4.
11. Iqbal N, Irfan M, Jabeen K, Kazmi MM, Tariq U. Chronic pulmonary mucormycosis: an emerging fungal infection in diabetes mellitus. 2017; 3(2): 121–5.
12. Jia MF, Liang LG, Zhu CLX. Successful Treatment of Ec- zema-Like Mucormycosis in a Child by Combination of In- travenous Drip and Percutaneous Injection Amphotericin B. Mycopathologia. 2019; 184(2): 309-13.
13. Ramı L, Rodrı E, Xicohtencatl-cortes J, Ramı JP. Primary Cu- taneous Mucormycosis Caused by Rhizopus oryzae: A Case Report and Review of Literature. 2016; 182; (3-4): 387-92.
14. Mishra S, Shelly D, Gupta D, Bharadwaj R. Invasive cutane-
ous mucormycosis in a preterm neonate presenting as a vesi-
cobullous lesion. 2018; 61(1): 103-5.
15. Universitario HG, Alicante D. Primary Cutaneous Mucormy-
cosis Due to Rhizopus arrhizus in an 8-Year-Old Girl Mu- cormicosis cutánea primaria por Rhizopus arrhizus en una ni. 2011; 109(6): 562–4.
16. Ertugrul MB, Arikan-akdagli S. Mucormycosis. dalam: Emerging Infectious Diseases. Philadelphia: Academic Press; 2014.h. 309-22.
17. Shiraishi K, Sasaki S, Sadamoto Y. Cutaneous mucormycosis in a patient with acute lymphocytic leukemia. Eu J Dermatol. 2014; 24(1): 116–7.
18. Cornely OA, Alastruey-izquierdo A, Arenz D, Chen SCA, Dannaoui E, Hochhegger B, dkk. Review Global guideline for the diagnosis and management of mucormycosis: an ini- tiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium. 2019; 3099(19): 1–17.
19. Challa S. Mucormycosis: Pathogenesis and Pathology. 2019; 13(1): 11-20.
20. Francis JR, Villanueva P, Bryant P, Blyth CC. Mucormyco- sis in Children : Review and Recommendations for Manage-
ment. J Pediatric Infect Dis. 2018; 7(2):159-64.
21. Ibrahim AS, Spellberg B, Walsh TJ, Kontoyiannis DP. Patho-
genesis of Mucormycosis. 2012; 54(1): 1–7.
22. Abidi MZ, Sohail MR, Cummins N, Wilhelm M, Wengenack
N, Brumble L, dkk. Stability in the cumulative incidence, se- verity and mortality of 101 cases of invasive mucormycosis in high risk patients from 1995 to 2021 : a comparison of eras immediately before and after the availability of variconazole and echinocandin-amphotericin combination therapies. 2014; 57(11): 687–98.
23. Garbino J, Myers C, Ambrosioni J, Gumy-pause F. Report of a Successful Treatment of Pulmonary Cunninghamella bertholletiae Infection With Liposomal Amphotericin and Posaconazole in a Child With GvHD and Review of the Lit- erature. 2010; 32(2): 85–7.
24. Cornely OA, Dannaoui E, Groll AH, Lagrou K, Chakrabar- ti A, Lanternier F, dkk. ESCMID and ECMM joint clinical guidelines for the diagnosis and management of mucormyco- sis 2013. 2014; 20(3): 5–26.

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Published
2023-04-12
How to Cite
Febriani, D., & Widhiati, S. (2023). MUKORMIKOSIS KUTAN PADA ANAK: TINJAUAN PUSTAKA. Media Dermato-Venereologica Indonesiana, 49(3), 173–181. https://doi.org/10.33820/mdvi.v49i3.308
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Tinjauan Pustaka